Time:2015-06-12 10:00:00

Place:Ruth Mulan Chu Chao Building Room A1006

Host:LI Yinfeng

Reporter:LI Xuejin

Content

Dissipative particle dynamics (DPD) is a particle-based Lagrangian method for simulating dynamic and rheological properties of simple and complex fluids at mesoscopic length and time scales. In this talk, we shall discuss the use of DPD method to study the mechanics, rheology and dynamics of physical and biological systems. We cover the traditional one-component whole-cell model but also a novel two-component whole-cell model used to simulate the interactions between the lipid bilayer and the cytoskeletal network of human red blood cells. We highlight examples of successful simulations of hematological disorders including malaria and sickle cell anemia. Specific applications on modeling shape transformation of membrane vesicles will also be presented.